https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36824 Wed 17 Nov 2021 16:29:09 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25052 Bacteroidales family S24-7 is a prominent example of one of these groups. Marker gene surveys indicate that members of this family are highly localized to the gastrointestinal tracts of homeothermic animals and are increasingly being recognized as a numerically predominant member of the gut microbiota; however, little is known about the nature of their interactions with the host. Results: Here, we provide the first whole genome exploration of this family, for which we propose the name "Candidatus Homeothermaceae," using 30 population genomes extracted from fecal samples of four different animal hosts: human, mouse, koala, and guinea pig. We infer the core metabolism of "Ca. Homeothermaceae" to be that of fermentative or nanaerobic bacteria, resembling that of related Bacteroidales families. In addition, we describe three trophic guilds within the family, plant glycan (hemicellulose and pectin), host glycan, and a-glucan, each broadly defined by increased abundance of enzymes involved in the degradation of particular carbohydrates. Conclusions: "Ca. Homeothermaceae" representatives constitute a substantial component of the murine gut microbiota, as well as being present within the human gut, and this study provides important first insights into the nature of their residency. The presence of trophic guilds within the family indicates the potential for niche partitioning and specific roles for each guild in gut health and dysbiosis.]]> Wed 11 Apr 2018 15:06:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39312 Proteobacteria and Actinobacteria were identified as the two dominant phyla in the remediation of diesel contaminated soil. Metagenomics analysis revealed that the preferred metabolic pathway of nitrogen was from ammonium to glutamate via glutamine, and the enzymes governing this transformation were glutamine synthetase and glutamate synthetase; while in nitrate based amendment, the conversion from nitrite to ammonium was restrained by the low abundance of nitrite reductase enzyme and therefore retarded the TPH degradation rate. It is concluded that during the process of nitrogen enhanced bioremediation, the most efficient nitrogen cycling direction was from ammonium to glutamine, then to glutamate, and finally joined with carbon metabolism after transforming to 2-oxoglutarate.]]> Wed 10 Aug 2022 11:08:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54464 Tue 27 Feb 2024 13:53:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38873 Bacteroides species and describe the antimicrobial resistance biogeography along the intestine. We also detail which species, at which locations, are involved with the tryptophan/indole pathway, whose malfunctioning has been linked to pathologies including inflammatory bowel disease. Our study thus provides invaluable resources for investigating mechanisms connecting gut microbiota and host pathophysiology.]]> Tue 22 Feb 2022 16:36:25 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53306 Tue 21 Nov 2023 12:03:02 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49092 Thu 04 May 2023 15:02:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55037 Thu 04 Apr 2024 13:20:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19535 Sat 24 Mar 2018 08:02:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24705 Escherichia coli DH5α cells. Based on the results, all three genes were actively expressed and their products could act on their corresponding substrates.]]> Sat 24 Mar 2018 07:10:56 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41064 Mon 08 Aug 2022 14:59:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55383 Fri 24 May 2024 10:35:40 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46954 Genomoviridae) are circular single-stranded DNA viruses that have been mainly identified through metagenomics studies in a wide variety of samples from various environments. Here, we describe 98 genomes of genomoviruses found associated with members of 19 plant families from Australia, Brazil, France, South Africa and the USA. These 98 genomoviruses represent 29 species, 26 of which are new, in the genera Gemykolovirus (n = 37), Gemyduguivirus (n = 9), Gemygorvirus (n = 8), Gemykroznavirus (n = 6), Gemycircularvirus (n = 21) and Gemykibivirus (n = 17).]]> Fri 09 Dec 2022 15:59:25 AEDT ]]>